Post-transcriptional control: mRNA translation, localization and turnover

Topics: Biochemistry, Keywords: see below

Date: /8/9/10/ June 2010, Edinburgh, United Kingdom, Europe

Web Site, Contact: elizabeth.faircliffe [at] biochemistry.org

  

Official Information:

Meeting Background:

The importance of post-transcriptional regulation in the cytoplasm is highlighted by recently increased estimates of the numbers of genes that are subject to these forms of control and by the number of diseases that are linked to the misregulated post-transcriptional gene expression. Indeed it is becoming increasingly apparent that the processes of mRNA translation, localization and turnover are closely intertwined and should not be studied in isolation. Consistent with this, the increasing understanding of miRNA-mediated regulation implicates the intimate coupling of multiple levels of post-transcriptional control.

There is a large, constantly expanding scientific community in the UK whose work focuses on mRNA translation and/or aspects of mRNA localization and turnover. However their work touches upon diverse aspects of biology such as metabolism, immunity, neuroscience, reproduction and viral lifecycle regulation and, consequently, they do not have the opportunity to come together at meetings to present and discuss their work. This meeting will provide an exciting forum for such researchers who utilize varying combinations of animal models, cellular, genetic, biochemical and molecular biological approaches to the study of a wide variety of diseases and basic processes but whose foundation hinges on post-transcriptional control of gene expression.

We strongly encourage scientists with specific interests in post-transcriptional control or a general interest in the regulation of gene expression to attend. The majority of the talks will be selected from submitted abstracts and we particularly encourage early-stage researchers and post-graduate students to submit abstracts for consideration for oral presentation.

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