Intrinsically Disordered Proteins in Biomedicine

Topics: Biochemistry, Medicinal Chemistry, Supramolecular Chemistry, Keywords: Unfolded Proteins, NMR, SAXS, Bioinformatics, Biomedicine

Date: /4/5/6/ October 2010, Barcelona, Spain, Europe

Web Site, Contact: biomed@irbbarcelona.org

  

Official Information:

Intrinsically disordered proteins are Nature’s response to the increased
complexity of higher organisms and are associated with diseases such as Cancer
and Neurodegeneration. Genome sequencing projects and bioinformatics analyses
have shown that disordered proteins are highly abundant in eukaryotes and are
tightly regulated. Enabling technologies that offer structural information in
solution, such as Nuclear Magnetic Resonance, Small Angle X-ray scattering, and
single molecule fluorescence, are providing novel insights into the structural
propensities and interactions of disordered proteins. A new paradigm, in which
dynamic averaging of conformational ensembles is central, is emerging for the
structural and functional analysis of disordered proteins.

This conference gathers together some of the major contributors to the
development of this field to analyze the current ideas and future avenues of
research in a multidisciplinary, think-tank atmosphere.

Organised by IRB Barcelona with the collaboration of the Banco Bilbao Vizcaya
Argentaria Foundation (fBBVA).

Registration deadline: July 15, 2010

There is no registration fee for this conference, but the number of participants
is limited.

Participants are invited to submit abstracts, a number of which will be selected
for short talk and poster presentations. Abstracts should include a title,
authors, affiliations, summary (max 250 words) and references.