Inflammation 2010

Topics: Biochemistry, Medicinal Chemistry, Keywords: Inflammation, PAH, GPCR

Date: /18/ November 2010, Stevenage, United Kingdom, Europe

Web Site, Contact: maggi [at] maggichurchouseevents.co.uk (Mrs Maggi Churchouse)

  

Official Information:

Introduction

The objective of the meeting is to bring together scientists with an interest in inflammation research, and to encourage the communication and discussion of recent advances and results – ranging from early research findings to clinical data. Attendees will hear from world-class speakers who will be discussing new therapeutic approaches for the treatment of the wide range of serious diseases driven by underlying inflammatory processes.

Programme

09.00 Registration and refreshments

09.25 Introduction

09.30 Epigenetic modulation for the future treatment of inflammatory disease

Prof Peter Barnes, Imperial College London

10.30 Identification of potent and selective molecule inhibitors of the BET family bromodomains demonstrate the tractability of a new class of epigenetic targets for drug discovery

Dr Jason Witherington (Epinova DPU, GlaxoSmithKline R&D)

11.10 Refreshments

11.40 Agonism at prostacyclin receptors in the treatment of PAH

Keith J Morrison (Actelion)

12.20 Identification of ALK5 inhibitors for the treatment of PAH

Dr Duncan Shaw (Novartis Institutes for Biomedical Research)

13.00 Lunch

14.00 The discovery of novel TLR7 agonists

Roger Bonnert (AstraZeneca)

14.40 Allosteric modulation beyond GPCRs: applications to inflammation disease targets

Dr Laurent Galibert (Addex Pharmaceuticals)

15.20 Refreshments

15:50 The discovery of CDP323, a novel and potent Inhibitor of the integrins α4β1 (VLA-4) and α4β7

Julien Brown (UCB)

16.30 Generation and development of a series of MAPKAPK5 inhibitors for the treatment of rheumatoid arthritis

Martin Andrews (Galapagos)

17.10 Close

Application and Fees

Application should be made before 18th October to avoid the late fee. Please register via the website or by using the flier application form (available from the website). Registration fees range from £40 to £161, and early bird fees are available until 31st August.