Designing safer medicines in discovery: current and emerging opportunities

Topics: Medicinal Chemistry, Toxicology, Keywords: Safety, Prediction, Drug Discovery, Attrition

Date: /17/ March 2011, London, United Kingdom, Europe

Web Site, Contact: conferences@soci.org

  

Official Information:

This meeting will look at how better Clinical Candidates can be designed in Drug Discovery with an enhanced awareness of potential future safety issues. The emphasis will be on what scientists can do immediately to reduce attrition due to safety and what is coming on the 2-4 year horizon. Following the focus on pharmacokinetics and drug metabolism in the discovery process during the 1990’s, the causes of this attrition have shifted, with drug toxicity accounting for a significant proportion of drug failures. This has led to an increased focus on developing improved preclinical safety screening strategies and compound design principles and this meeting will provide practical insights into some of the recent improvements and future directions in this key area.